3NP9
Glycogen phosphorylase complexed with 3-(beta-D-glucopyranosyl)-2-hydroxy-5-methoxy-chlorobenzene
Summary for 3NP9
Entry DOI | 10.2210/pdb3np9/pdb |
Related | 3NP7 3NPA |
Descriptor | Glycogen phosphorylase, muscle form, (1S)-1,5-anhydro-1-(3-chloro-2-hydroxy-5-methoxyphenyl)-D-glucitol (3 entities in total) |
Functional Keywords | glycogenolysis, type 2 diabetes, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) |
Total number of polymer chains | 1 |
Total formula weight | 97840.04 |
Authors | Alexacou, K.-M. (deposition date: 2010-06-28, release date: 2011-06-08, Last modification date: 2023-11-22) |
Primary citation | Alexacou, K.M.,Zhang, Y.Z.,Praly, J.P.,Zographos, S.E.,Chrysina, E.D.,Oikonomakos, N.G.,Leonidas, D.D. Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase. Bioorg.Med.Chem., 19:5125-5136, 2011 Cited by PubMed: 21821421DOI: 10.1016/j.bmc.2011.07.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.999 Å) |
Structure validation
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