3NID
The Closed Headpiece of Integrin alphaIIB beta3 and its Complex with an alpahIIB beta3 -Specific Antagonist That Does Not Induce Opening
Summary for 3NID
Entry DOI | 10.2210/pdb3nid/pdb |
Related | 2VDR 3NID 3NIF 3NIG |
Descriptor | Integrin alpha-IIb, SULFATE ION, MAGNESIUM ION, ... (13 entities in total) |
Functional Keywords | integrin, headpiece, alphaiib, beta3, cell adhesion-blood clotting complex, cell adhesion/blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 302255.43 |
Authors | Zhu, J.H.,Zhu, J.Q.,Springer, T.A. (deposition date: 2010-06-15, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Zhu, J.H.,Zhu, J.Q.,Negri, A.,Provasi, D.,Filizola, M.,Coller, B.S.,Springer, T.A. Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening. Blood, 116:5050-5059, 2010 Cited by PubMed: 20679525DOI: 10.1182/blood-2010-04-281154 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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