3NIG
The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening
Summary for 3NIG
Entry DOI | 10.2210/pdb3nig/pdb |
Related | 2VDR 3NID 3NIF |
Descriptor | Integrin alpha-IIb, MAGNESIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | integrin, headpiece, alphaiib, beta3, cell adhesion-immune system complex, cell adhesion-blood clotting complex, cell adhesion/blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 300994.33 |
Authors | Zhu, J.H.,Zhu, J.Q.,Springer, T.A. (deposition date: 2010-06-15, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Zhu, J.,Zhu, J.,Negri, A.,Provasi, D.,Filizola, M.,Coller, B.S.,Springer, T.A. Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening. Blood, 116:5050-5059, 2010 Cited by PubMed: 20679525DOI: 10.1182/blood-2010-04-281154 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report