3MKP
Crystal structure of 1K1 mutant of Hepatocyte Growth Factor/Scatter Factor fragment NK1 in complex with heparin
Summary for 3MKP
Entry DOI | 10.2210/pdb3mkp/pdb |
Related | 1BHT 1GMN 1GMO 1GP9 1NK1 |
Descriptor | Hepatocyte growth factor, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SULFATE ION, ... (6 entities in total) |
Functional Keywords | growth factor, supramolecular assembly, hgf/sf, met receptor, nk1, hormone |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 87891.49 |
Authors | Gherardi, E.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2010-04-15, release date: 2010-08-18, Last modification date: 2023-11-01) |
Primary citation | Gherardi, E.,Chirgadze, D.Y.,Bocci, M.,Brocchieri, C.,Bevan, D.,Kajstura, J.,Esposito, G.,Lietha, D.,Rota, M.,Leri, A.,Mallorqui-Fernandez, N.,Bandyopadhyay, A.,Youles, M.,Mulloy, B.,Rowe, A.,Alison, M.,Edwards, D.,Vannini, V.,Blundell, T.,Anversa, P. Engineering a fragment of Hepatocyte Growth Factor/Scatter Factor for tissue and organ regeneration To be Published, |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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