3L2J
Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)
Summary for 3L2J
Entry DOI | 10.2210/pdb3l2j/pdb |
Related | 3C4M 3H3G |
Related PRD ID | PRD_900001 |
Descriptor | Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (2 entities in total) |
Functional Keywords | dimer, extracellular domain, mbp fusion protein, periplasm, sugar transport, transport, cell membrane, disease mutation, disulfide bond, dwarfism, g-protein coupled receptor, glycoprotein, membrane, receptor, transducer, transmembrane, membrane protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 120391.27 |
Authors | Pioszak, A.A.,Xu, H.E. (deposition date: 2009-12-15, release date: 2010-02-02, Last modification date: 2023-09-06) |
Primary citation | Pioszak, A.A.,Harikumar, K.G.,Parker, N.R.,Miller, L.J.,Xu, H.E. Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation. J.Biol.Chem., 285:12435-12444, 2010 Cited by PubMed: 20172855DOI: 10.1074/jbc.M109.093138 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.24 Å) |
Structure validation
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