3L2J

Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor	polymer	535	59853.3	2	UniProt (P0AEX9) UniProt (Q03431) Pfam (PF01547) Pfam (PF02793)	Escherichia coli	MMBP, Maltodextrin-binding protein, Parathyroid hormone 1 receptor, PTH1 receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor
2	C, D (C, D)	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	2	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose

Sequence modifications

A, B: -341 - 22 (UniProt: P0AEX9)

PDB	External Database	Details
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag

A, B: 29 - 187 (UniProt: Q03431)

PDB	External Database	Details
Asn 23	-	linker
Ala 24	-	linker
Ala 25	-	linker
Ala 26	-	linker
Glu 27	-	linker
Phe 28	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119706.7
Branched	Number of molecules	2
	Total formula weight	684.6
All*	Total formula weight	120391.3

*Water molecules are not included.