3KTU

Structure of human 8-oxoGuanine Glycosylase 1 bound to fluorninated oxoG-containing DNA

Summary for 3KTU

• Entry DOI: 10.2210/pdb3ktu/pdb
• Related: 1EBM 3IH7
• Descriptor: N-glycosylase/DNA lyase, DNA (5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*AP*(FDG)P*GP*TP*CP*TP*AP*C)-3'), ... (5 entities in total)
• Functional Keywords: 8-oxoguanine, 2'-fluoro-8-oxoguanine, protein-dna complex, dna glycosylase, base excsion repair, dna damage, dna repair, hydrolase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
• Total number of polymer chains: 3
• Total formula weight: 43496.62

Authors

Verdine, G.L.,Lee, S.M. (deposition date: 2009-11-26, release date: 2010-07-14, Last modification date: 2023-09-06)

• Primary citation: Verdine, G.L.,Lee, S.M.; Structural investigation of hOGG1 bound to a fluorinated oxoG analog; to be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)