3INC

Crystal structure of human insulin with Ni+2 complex

Summary for 3INC

• Entry DOI: 10.2210/pdb3inc/pdb
• Related: 1MSO 1os4 2R34 2R35 2R36 3INS
• Descriptor: Insulin A chain, Insulin B chain, NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: insulin, conformational state, metal binding, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 4
• Total formula weight: 11752.69

Authors

Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-12, release date: 2010-08-18, Last modification date: 2023-11-01)

• Primary citation: Raghavendra, N.,Pattabhi, V.,Rajan, S.S.; Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)