3H6F
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor HT1171
Summary for 3H6F
Entry DOI | 10.2210/pdb3h6f/pdb |
Related | 2FHG 2FHH 3H6I |
Descriptor | Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB, DIMETHYLFORMAMIDE, ... (4 entities in total) |
Functional Keywords | binding sites, oxazolidin-2-one, mycobacterium tuberculosis, protease inhibitors, proteasome endopeptidase complex, protein subunits, substrate specificity, hydrolase, proteasome |
Biological source | Mycobacterium tuberculosis More |
Cellular location | Cytoplasm (By similarity): O33244 O33245 |
Total number of polymer chains | 28 |
Total formula weight | 735855.46 |
Authors | |
Primary citation | Lin, G.,Li, D.,de Carvalho, L.P.,Deng, H.,Tao, H.,Vogt, G.,Wu, K.,Schneider, J.,Chidawanyika, T.,Warren, J.D.,Li, H.,Nathan, C. Inhibitors selective for mycobacterial versus human proteasomes. Nature, 461:621-626, 2009 Cited by PubMed: 19759536DOI: 10.1038/nature08357 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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