3H6F

Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor HT1171

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, B, D, F... (A, B, D, F, I...)	Proteasome (Alpha subunit) PrcA	polymer	248	26911.0	14	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1)	Mycobacterium tuberculosis
2	BA, C, E, G, H... (C, E, G, H, J...)	Proteasome (Beta subunit) PrcB	polymer	240	25300.3	14	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9)	Mycobacterium tuberculosis	Proteasome, beta subunit
3	AB, AC, BB, BC, CA... (J, V, A, K, W...)	DIMETHYLFORMAMIDE	non-polymer		73.1	67	Chemie (DMF)
4	AD, BD, CD, DD, ED... (J, K, L, M, N...)	water	water		18.0	1749	Chemie (HOH)

Sequence modifications

C, E, G, H, J, L, N, P, R, T, V, X, Z, 2: 302 - 534 (UniProt: O33245)

PDB	External Database	Details
Ozt 301	-	insertion
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	730958.2
Non-Polymers*	Number of molecules	67
	Total formula weight	4897.3
All*	Total formula weight	735855.5

*Water molecules are not included.