3G7V
Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein
Summary for 3G7V
| Entry DOI | 10.2210/pdb3g7v/pdb |
| Related | 3G7W |
| Related PRD ID | PRD_900001 |
| Descriptor | Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | native fold for amyloidogenic protein, sugar transport, transport, amidation, amyloid, cleavage on pair of basic residues, hormone, secreted, sugar binding protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 4 |
| Total formula weight | 181039.29 |
| Authors | Wiltzius, J.J.W.,Sawaya, M.R.,Eisenberg, D. (deposition date: 2009-02-10, release date: 2009-06-23, Last modification date: 2023-09-06) |
| Primary citation | Wiltzius, J.J.,Sievers, S.A.,Sawaya, M.R.,Eisenberg, D. Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18:1521-1530, 2009 Cited by PubMed: 19475663DOI: 10.1002/pro.145 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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