3G7V

Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005179	molecular_function	hormone activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	0071702	biological_process	organic substance transport
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0005179	molecular_function	hormone activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0006974	biological_process	DNA damage response
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	0071702	biological_process	organic substance transport
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex
C	0005179	molecular_function	hormone activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0006974	biological_process	DNA damage response
C	0008643	biological_process	carbohydrate transport
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	0071702	biological_process	organic substance transport
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex
D	0005179	molecular_function	hormone activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0006974	biological_process	DNA damage response
D	0008643	biological_process	carbohydrate transport
D	0015144	molecular_function	carbohydrate transmembrane transporter activity
D	0015768	biological_process	maltose transport
D	0016020	cellular_component	membrane
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0034219	biological_process	carbohydrate transmembrane transport
D	0034289	biological_process	detection of maltose stimulus
D	0042597	cellular_component	periplasmic space
D	0042956	biological_process	maltodextrin transmembrane transport
D	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	0055085	biological_process	transmembrane transport
D	0060326	biological_process	cell chemotaxis
D	0071702	biological_process	organic substance transport
D	1901982	molecular_function	maltose binding
D	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS00258
Number of Residues	15
Details	CALCITONIN Calcitonin / CGRP / IAPP family signature. CNT.ATCAtqrLanfL

Chain	Residue	Details
A	CYS372-LEU386

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site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO107-ASN124

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Tyrosine amide => ECO:0000269|PubMed:2651160, ECO:0000269|PubMed:3053705

Chain	Residue	Details
A	TYR407
B	TYR407
C	TYR407
D	TYR407

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