3FMM

P38 kinase crystal structure in complex with RO6226

Summary for 3FMM

• Entry DOI: 10.2210/pdb3fmm/pdb
• Related: 3FLN 3FLS 3FLW 3FLY 3FLZ 3FMH 3FMJ 3FMK 3FML 3FMN
• Descriptor: Mitogen-activated protein kinase 14, 6-(2,4-difluorophenoxy)-N-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine (3 entities in total)
• Functional Keywords: p38; map kinase; serine/threonine kinase, atp-binding, kinase, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43132.09

Authors

Kuglstatter, A.,Ghate, M. (deposition date: 2008-12-22, release date: 2009-12-22, Last modification date: 2023-09-06)

• Primary citation: Soth, M.,Kuglstatter, A.,Gabriel, T.; P38 kinase crystal structure in complex with RO6226; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)