3F6K
Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with neurotensin
Summary for 3F6K
Entry DOI | 10.2210/pdb3f6k/pdb |
Descriptor | Sortilin, Neurotensin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | protein sorting receptor, 10-bladed beta-propeller, cys-rich domains, ssortilin, sortilin vps10p-d, protein-peptide complex, developmental protein, differentiation, endocytosis, endoplasmic reticulum, endosome, glycoprotein, golgi apparatus, lysosome, membrane, phosphoprotein, receptor, transmembrane, transport, cytoplasmic vesicle, secreted, signaling protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 79703.86 |
Authors | Quistgaard, E.M.,Madsen, P.,Groftehauge, M.K.,Nissen, P.,Petersen, C.M.,Thirup, S. (deposition date: 2008-11-06, release date: 2008-12-30, Last modification date: 2023-12-27) |
Primary citation | Quistgaard, E.M.,Madsen, P.,Groftehauge, M.K.,Nissen, P.,Petersen, C.M.,Thirup, S.S. Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain. Nat.Struct.Mol.Biol., 16:96-98, 2009 Cited by PubMed: 19122660DOI: 10.1038/nsmb.1543 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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