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3EZQ

Crystal Structure of the Fas/FADD Death Domain Complex

Summary for 3EZQ
Entry DOI10.2210/pdb3ezq/pdb
DescriptorTumor necrosis factor receptor superfamily member 6, Protein FADD, SULFATE ION, ... (5 entities in total)
Functional Keywordsapoptosis, disc, fas, fadd, membrane, receptor, transmembrane
Biological sourceHomo sapiens (Human)
More
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted. Isoform 6: Secreted: P25445
Total number of polymer chains16
Total formula weight217475.48
Authors
Schwarzenbacher, R.,Robinson, H.,Stec, B.,Riedl, S.J. (deposition date: 2008-10-23, release date: 2008-12-23, Last modification date: 2023-12-27)
Primary citationScott, F.L.,Stec, B.,Pop, C.,Dobaczewska, M.K.,Lee, J.J.,Monosov, E.,Robinson, H.,Salvesen, G.S.,Schwarzenbacher, R.,Riedl, S.J.
The Fas-FADD death domain complex structure unravels signalling by receptor clustering
Nature, 457:1019-1022, 2009
Cited by
PubMed: 19118384
DOI: 10.1038/nature07606
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.73 Å)
Structure validation

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