3ERD
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
Replaces: 2ERDSummary for 3ERD
Entry DOI | 10.2210/pdb3erd/pdb |
Descriptor | ESTROGEN RECEPTOR ALPHA, GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | nuclear receptor, transcription factor, estrogen, agonist, coactivator |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 63552.42 |
Authors | Shiau, A.K.,Barstad, D.,Loria, P.M.,Cheng, L.,Kushner, P.J.,Agard, D.A.,Greene, G.L. (deposition date: 1999-03-31, release date: 1999-04-08, Last modification date: 2023-09-06) |
Primary citation | Shiau, A.K.,Barstad, D.,Loria, P.M.,Cheng, L.,Kushner, P.J.,Agard, D.A.,Greene, G.L. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell(Cambridge,Mass.), 95:927-937, 1998 Cited by PubMed: 9875847DOI: 10.1016/S0092-8674(00)81717-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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