3EAJ
Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with two molecules in one asymmetric unit
Summary for 3EAJ
Entry DOI | 10.2210/pdb3eaj/pdb |
Related | 3E91 3EA7 3EA8 3EA9 |
Descriptor | 3C-like proteinase (2 entities in total) |
Functional Keywords | sars coronavirus main protease mutant extra helical domain, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger |
Biological source | SARS coronavirus (SARS-CoV) |
Cellular location | Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8 |
Total number of polymer chains | 2 |
Total formula weight | 67424.88 |
Authors | Shi, J.H.,Jayaraman, S.,Song, J.X. (deposition date: 2008-08-26, release date: 2009-09-01, Last modification date: 2023-11-01) |
Primary citation | Shi, J.H.,Jayaraman, S.,Song, J.X. crystal structure of SARS-CoV Mpro mutant with two molecules one ASU To be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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