3EA9

Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with one molecule in one asymmetric unit

Summary for 3EA9

• Entry DOI: 10.2210/pdb3ea9/pdb
• Related: 3E91 3EA7 3EA8 3EAJ
• Descriptor: 3C-like proteinase (2 entities in total)
• Functional Keywords: sars coronavirus main protease mutant, 3c-like protease, extra helical domain, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• Biological source: SARS coronavirus (SARS-CoV)
• Cellular location: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8
• Total number of polymer chains: 1
• Total formula weight: 33712.44

Authors

Shi, J.H.,Jayaraman, S.,Song, J.X. (deposition date: 2008-08-25, release date: 2009-09-01, Last modification date: 2023-11-01)

• Primary citation: Shi, J.H.,Jayaraman, S.,Song, J.X.; crystal structure of SARS-CoV Mpro quadruple mutant; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)