3EA7

Crystal structure of SARS-CoV main protease triple mutant STI/A in space group P21

Summary for 3EA7

• Entry DOI: 10.2210/pdb3ea7/pdb
• Related: 3E91 3EA8 3EA9 3EAJ
• Descriptor: 3C-like proteinase (2 entities in total)
• Functional Keywords: sars-cov main protease mutant, 3c-like protease mutant, extra helical domain mutation, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• Biological source: SARS coronavirus (SARS-CoV)
• Cellular location: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8
• Total number of polymer chains: 2
• Total formula weight: 67577.07

Authors

Shi, J.H.,Jayaraman, S.,Song, J.X. (deposition date: 2008-08-25, release date: 2009-09-01, Last modification date: 2023-11-01)

• Primary citation: Shi, J.H.,Jayaraman, S.,Song, J.X.; Crystal structure of SARS-CoV Mpro mutant; To be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)