3EA7

Crystal structure of SARS-CoV main protease triple mutant STI/A in space group P21

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase	polymer	306	33788.5	2	UniProt (P0C6U8) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7)	SARS coronavirus (SARS-CoV)	SARS-CoV main protease, 3CL-PRO, 3CLp, nsp5
2	C, D (A, B)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A, B: 1 - 306 (UniProt: P0C6U8)

PDB	External Database	Details
Ala 284	Ser 3524	engineered mutation
Ala 285	Thr 3525	engineered mutation
Ala 286	Ile 3526	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67577.1
All*	Total formula weight	67577.1

*Water molecules are not included.