3EAJ
Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with two molecules in one asymmetric unit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase | polymer | 306 | 33712.4 | 2 | UniProt (P0C6U8) Pfam (PF05409) UniProt (by SIFTS) (P0C6X7) | SARS coronavirus (SARS-CoV) | SARS-CoV main protease, 3CL-PRO, 3CLp, nsp5 |
| 2 | C, D (A, B) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Ala 284 | Ser 3524 | engineered mutation |
| Ala 285 | Thr 3525 | engineered mutation |
| Ala 286 | Ile 3526 | engineered mutation |
| Ala 291 | Phe 3531 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67424.9 | |
| All* | Total formula weight | 67424.9 |
