3D12

Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3

Summary for 3D12

Entry DOI	10.2210/pdb3d12/pdb
Related	3D11
Descriptor	Hemagglutinin-neuraminidase, Ephrin-B3, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	beta propeller, protein-receptor complex, envelope protein, glycoprotein, hemagglutinin, hydrolase, membrane, signal-anchor, transmembrane, virion, developmental protein, differentiation, neurogenesis, hydrolase-membrane protein complex, hydrolase/membrane protein
Biological source	Nipah virus More
Cellular location	Virion membrane ; Single-pass type II membrane protein : Q9IH62 Membrane; Single-pass type I membrane protein: O35393
Total number of polymer chains	4
Total formula weight	135759.82
Authors	Xu, K.,Rajashankar, K.R.,Chan, Y.P.,Himanen, P.,Broder, C.C.,Nikolov, D.B. (deposition date: 2008-05-02, release date: 2008-08-19, Last modification date: 2020-07-29)
Primary citation	Xu, K.,Rajashankar, K.R.,Chan, Y.P.,Himanen, J.P.,Broder, C.C.,Nikolov, D.B. Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105:9953-9958, 2008 Cited by PubMed: 18632560 DOI: 10.1073/pnas.0804797105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.005 Å)

Structure validation