3BOW
Structure of M-calpain in complex with Calpastatin
Summary for 3BOW
Entry DOI | 10.2210/pdb3bow/pdb |
Related | 1df0 1kfu 1kxr |
Descriptor | Calpain-2 catalytic subunit, Calpain small subunit 1, Calpastatin, ... (5 entities in total) |
Functional Keywords | cysteine protease, inhibitor, cell membrane, hydrolase, membrane, protease, thiol protease, phosphoprotein, protease inhibitor, thiol protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cytoplasm (By similarity): Q07009 Cytoplasm: Q64537 |
Total number of polymer chains | 3 |
Total formula weight | 114049.26 |
Authors | Hanna, R.A.,Campbell, R.L.,Davies, P.L. (deposition date: 2007-12-17, release date: 2008-11-25, Last modification date: 2023-08-30) |
Primary citation | Hanna, R.A.,Campbell, R.L.,Davies, P.L. Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin. Nature, 456:409-412, 2008 Cited by PubMed: 19020623DOI: 10.1038/nature07451 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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