3BHH

Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)

Summary for 3BHH

• Entry DOI: 10.2210/pdb3bhh/pdb
• Descriptor: Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile (3 entities in total)
• Functional Keywords: camk2b, cam2, camk2, cam kinase ii beta chain, camk ii beta subunit, calcium/calmodulion dependent protein kinase ii beta, ec:2.7.1.123, mgc29528, proline rich calmodulin dependent protein kinase, structural genomics consortium, sgc, atp-binding, calmodulin-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 134979.33

Authors

Filippakopoulos, P.,Rellos, P.,Niesen, F.,Burgess, N.,Bullock, A.,Berridge, G.,Pike, A.C.W.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-11-28, release date: 2007-12-11, Last modification date: 2023-08-30)

• Primary citation: Filippakopoulos, P.,Rellos, P.,Niesen, F.,Burgess, N.,Bullock, A.,Berridge, G.,Pike, A.C.W.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.; Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)