3BHH
Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Calcium/calmodulin-dependent protein kinase type II beta chain | polymer | 295 | 33564.6 | 4 | UniProt (Q13554) Pfam (PF00069) | Homo sapiens (human) | CaM-kinase II beta chain, CaM kinase II subunit beta, CaMK-II subunit beta |
| 2 | E, F (A, B) | [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile | non-polymer | 360.4 | 2 | Chemie (5CP) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 303 (UniProt: Q13554)
| PDB | External Database | Details |
|---|---|---|
| Ser 9 | - | expression tag |
| Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 134258.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 720.8 | |
| All* | Total formula weight | 134979.3 |
