3BCM
Crystal Structure of The Unswapped Form of P19A/L28Q/N67D BS-RNase
Summary for 3BCM
Entry DOI | 10.2210/pdb3bcm/pdb |
Related | 3BCO 3BCP |
Descriptor | Seminal ribonuclease, PHOSPHATE ION (3 entities in total) |
Functional Keywords | domain swapping, bovine seminal ribonuclease, non covalent dimer, antitumor activity, allosteric enzyme, endonuclease, hydrolase, nuclease, secreted |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted: P00669 |
Total number of polymer chains | 2 |
Total formula weight | 27625.00 |
Authors | Merlino, A.,Ercole, C.,Picone, D.,Pizzo, E.,Mazzarella, L.,Sica, F. (deposition date: 2007-11-13, release date: 2008-02-12, Last modification date: 2023-11-01) |
Primary citation | Merlino, A.,Ercole, C.,Picone, D.,Pizzo, E.,Mazzarella, L.,Sica, F. The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme J.Mol.Biol., 376:427-437, 2008 Cited by PubMed: 18164315DOI: 10.1016/j.jmb.2007.11.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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