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3BCO

Crystal Structure of The Swapped FOrm of P19A/L28Q/N67D BS-RNase

Summary for 3BCO
Entry DOI10.2210/pdb3bco/pdb
Related3BCM 3BCP
DescriptorSeminal ribonuclease (2 entities in total)
Functional Keywordsdomain swapping, bovine seminal ribonuclease, non covalent dimer, antitumor activity, allosteric enzyme, endonuclease, hydrolase, secreted
Biological sourceBos taurus (cattle)
Cellular locationSecreted: P00669
Total number of polymer chains2
Total formula weight27245.12
Authors
Merlino, A.,Ercole, C.,Picone, D.,Pizzo, E.,Mazzarella, L.,Sica, F. (deposition date: 2007-11-13, release date: 2008-02-12, Last modification date: 2023-11-01)
Primary citationMerlino, A.,Ercole, C.,Picone, D.,Pizzo, E.,Mazzarella, L.,Sica, F.
The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376:427-437, 2008
Cited by
PubMed: 18164315
DOI: 10.1016/j.jmb.2007.11.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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