3B8Z

High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)

Summary for 3B8Z

Entry DOI	10.2210/pdb3b8z/pdb
Descriptor	protein ADAMTS-5, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	alpha/beta, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix : Q9UNA0
Total number of polymer chains	2
Total formula weight	49330.38
Authors	Shieh, H.-S.,Williams, J.M.,Mathis, K.J.,Tortorella, M.D.,Tomasselli, A. (deposition date: 2007-11-02, release date: 2007-12-11, Last modification date: 2021-10-20)
Primary citation	Shieh, H.S.,Mathis, K.J.,Williams, J.M.,Hills, R.L.,Wiese, J.F.,Benson, T.E.,Kiefer, J.R.,Marino, M.H.,Carroll, J.N.,Leone, J.W.,Malfait, A.M.,Arner, E.C.,Tortorella, M.D.,Tomasselli, A. High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2). J.Biol.Chem., 283:1501-1507, 2008 Cited by PubMed: 17991750 DOI: 10.1074/jbc.M705879200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation