3B2Z

Crystal Structure of ADAMTS4 (apo form)

Summary for 3B2Z

Entry DOI	10.2210/pdb3b2z/pdb
Descriptor	ADAMTS-4, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywords	metalloprotease, aggrecanase, cleavage on pair of basic residues, extracellular matrix, glycoprotein, hydrolase, metal-binding, secreted, zymogen
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix (By similarity): O75173
Total number of polymer chains	8
Total formula weight	274937.80
Authors	Mosyak, L.,Stahl, M.,Somers, W. (deposition date: 2007-10-19, release date: 2007-12-25, Last modification date: 2023-08-30)
Primary citation	Mosyak, L.,Georgiadis, K.,Shane, T.,Svenson, K.,Hebert, T.,McDonagh, T.,Mackie, S.,Olland, S.,Lin, L.,Zhong, X.,Kriz, R.,Reifenberg, E.L.,Collins-Racie, L.A.,Corcoran, C.,Freeman, B.,Zollner, R.,Marvell, T.,Vera, M.,Sum, P.E.,Lavallie, E.R.,Stahl, M.,Somers, W. Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5. Protein Sci., 17:16-21, 2008 Cited by PubMed: 18042673 DOI: 10.1110/ps.073287008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation