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2ZU3

Complex structure of CVB3 3C protease with TG-0204998

Summary for 2ZU3
Entry DOI10.2210/pdb2zu3/pdb
Related2ZTX 2ZTY 2ZTZ 2ZU1 2ZU2 2ZU4 2ZU5
Related PRD IDPRD_000568
Descriptor3C proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide (3 entities in total)
Functional Keywordsprotease-inhibitor complex, hydrolase, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman coxsackievirus
Total number of polymer chains1
Total formula weight20914.05
Authors
Lee, C.C.,Tsui, Y.C.,Wang, A.H.-J. (deposition date: 2008-10-12, release date: 2009-01-13, Last modification date: 2023-11-01)
Primary citationLee, C.C.,Kuo, C.J.,Ko, T.P.,Hsu, M.F.,Tsui, Y.C.,Chang, S.C.,Yang, S.,Chen, S.J.,Chen, H.C.,Hsu, M.C.,Shih, S.R.,Liang, P.H.,Wang, A.H.-J.
Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284:7646-7655, 2009
Cited by
PubMed: 19144641
DOI: 10.1074/jbc.M807947200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

221051

數據於2024-06-12公開中

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