2ZNV

Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer

2ZNV の概要

• エントリーDOI: 10.2210/pdb2znv/pdb
• 関連するPDBエントリー: 2ZNR
• 分子名称: AMSH-like protease, Ubiquitin, ZINC ION, ... (6 entities in total)
• 機能のキーワード: protein complex, metal binding protein, alternative splicing, hydrolase, metal-binding, metalloprotease, protease, ubl conjugation pathway, zinc, cytoplasm, nucleus, phosphoprotein, hydrolase-signaling protein complex, hydrolase/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 74743.01

構造登録者

Sato, Y.,Azusa, Y.,Yamagata, A.,Mimura, H.,Wang, X.,Yamashita, M.,Ookata, K.,Nureki, O.,Iwai, K.,Komada, M.,Fukai, S. (登録日: 2008-05-01, 公開日: 2008-09-02, 最終更新日: 2023-11-01)

• 主引用文献: Sato, Y.,Yoshikawa, A.,Yamagata, A.,Mimura, H.,Yamashita, M.,Ookata, K.,Nureki, O.,Iwai, K.,Komada, M.,Fukai, S.; Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains; Nature, 455:358-362, 2008; PubMed: 18758443; DOI: 10.1038/nature07254

実験手法

X-RAY DIFFRACTION (1.6 Å)