2ZHW

Exploring thrombin S3 pocket

Summary for 2ZHW

• Entry DOI: 10.2210/pdb2zhw/pdb
• Related: 2ZDA 2ZFS 2ZHD 2ZHE 3BIU 3BIV
• Related PRD ID: PRD_000588
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (6 entities in total)
• Functional Keywords: blood coagulation, hydrolase inhibitors, acute phase, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, protease inhibitor, serine protease inhibitor, sulfation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P09945
• Total number of polymer chains: 3
• Total formula weight: 35856.82

Authors

Brandt, T.,Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-02-08, release date: 2009-02-10, Last modification date: 2023-11-15)

• Primary citation: Brandt, T.,Baum, B.,Hangauer, D.,Heine, A.,Klebe, G.; Exploring thrombin S3 pocket; To be Published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)