2ZF0

Exploring Thrombin S1 Pocket

Summary for 2ZF0

• Entry DOI: 10.2210/pdb2zf0/pdb
• Related: 1H8D 1YPG 2ZC9 2ZDA 2ZDV
• Related PRD ID: PRD_000608
• Descriptor: Thrombin Light Chain, Thrombin Heavy Chain, Hirudin variant-1, ... (6 entities in total)
• Functional Keywords: blood clotting/hydrolase inhibitors, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, zymogen, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35708.65

Authors

Baum, B.,Heine, A.,Klebe, G. (deposition date: 2007-12-18, release date: 2008-11-04, Last modification date: 2024-10-30)

• Primary citation: Baum, B.,Hangauer, D.,Heine, A.,Klebe, G.; Exploring Thrombin S1 pocket; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)