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2ZDV

Exploring Thrombin S1 pocket

Summary for 2ZDV
Entry DOI10.2210/pdb2zdv/pdb
Related1H8D 1YPG 2ZC9 2ZDA
Related PRD IDPRD_000602
DescriptorThrombin Light Chain, Thrombin Heavy Chain, Hirudin variant-1, ... (7 entities in total)
Functional Keywordsblood clotting/hydrolase inhibitors, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, zymogen, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P01050
Total number of polymer chains3
Total formula weight35807.59
Authors
Baum, B.,Heine, A.,Klebe, G. (deposition date: 2007-11-29, release date: 2008-10-28, Last modification date: 2023-11-15)
Primary citationBaum, B.,Hangauer, D.,Heine, A.,Klebe, G.
Exploring Thrombin S1 pocket
To be Published,
Experimental method
X-RAY DIFFRACTION (1.72 Å)
Structure validation

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