2Z80

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

2Z80 の概要

• エントリーDOI: 10.2210/pdb2z80/pdb
• 関連するPDBエントリー: 2Z7X 2Z81 2Z82
• 分子名称: Toll-like receptor 2, Variable lymphocyte receptor B, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: tlr2, lipopeptide, innate immunity, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system
• 由来する生物種: Homo sapiens (human, inshore hagfish); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79641.52

構造登録者

Lee, J.O.,Jin, M.S.,Kim, S.E.,Heo, J.Y. (登録日: 2007-08-30, 公開日: 2007-09-25, 最終更新日: 2020-07-29)

• 主引用文献: Jin, M.S.,Kim, S.E.,Heo, J.Y.,Lee, M.E.,Kim, H.M.,Paik, S.G.,Lee, H.,Lee, J.O.; Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide; Cell(Cambridge,Mass.), 130:1071-1082, 2007; PubMed: 17889651; DOI: 10.1016/j.cell.2007.09.008

実験手法

X-RAY DIFFRACTION (1.8 Å)