2Z80
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Toll-like receptor 2, Variable lymphocyte receptor B | polymer | 353 | 39710.2 | 2 | UniProt (O60603) UniProt (Q4G1L2) Pfam (PF00560) Pfam (PF13855) | Homo sapiens (human inshore hagfish) | Toll/interleukin-1 receptor-like protein 4, CD282 antigen |
| 2 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 284 (UniProt: O60603)
A, B: 290 - 353 (UniProt: Q4G1L2)
| PDB | External Database | Details |
|---|---|---|
| Ser 285 | - | linker |
| Arg 286 | - | linker |
| Asn 287 | - | linker |
| Gln 288 | - | linker |
| Leu 289 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79420.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 79641.5 |
