2Z80
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001817 | biological_process | regulation of cytokine production |
| A | 0002224 | biological_process | toll-like receptor signaling pathway |
| A | 0002237 | biological_process | response to molecule of bacterial origin |
| A | 0002755 | biological_process | MyD88-dependent toll-like receptor signaling pathway |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0006955 | biological_process | immune response |
| A | 0016021 | cellular_component | integral component of membrane |
| A | 0034134 | biological_process | toll-like receptor 2 signaling pathway |
| A | 0045087 | biological_process | innate immune response |
| B | 0001817 | biological_process | regulation of cytokine production |
| B | 0002224 | biological_process | toll-like receptor signaling pathway |
| B | 0002237 | biological_process | response to molecule of bacterial origin |
| B | 0002755 | biological_process | MyD88-dependent toll-like receptor signaling pathway |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0006955 | biological_process | immune response |
| B | 0016021 | cellular_component | integral component of membrane |
| B | 0034134 | biological_process | toll-like receptor 2 signaling pathway |
| B | 0045087 | biological_process | innate immune response |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 48 |
| Details | Repeat: {"description":"LRR 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | Repeat: {"description":"LRR 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"LRR 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 54 |
| Details | Repeat: {"description":"LRR 9"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15173186","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17889651","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
