2Z1W
tRNA guanine transglycosylase TGT E235Q mutant in complex with BDI (2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE)
Summary for 2Z1W
Entry DOI | 10.2210/pdb2z1w/pdb |
Related | 1P0B 2OKO 2Z1V 2Z1X |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE, ... (5 entities in total) |
Functional Keywords | tgt, e235q mutant, bdi, bih, 2-butyl-5, 6-dihydro-1h-imidazo[4, 5-d]pyridazine-4, 7-dione, transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 44027.19 |
Authors | Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K. (deposition date: 2007-05-16, release date: 2007-11-06, Last modification date: 2023-11-01) |
Primary citation | Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K. Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies J.Mol.Biol., 374:764-776, 2007 Cited by PubMed: 17949745DOI: 10.1016/j.jmb.2007.09.062 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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