2Z1W
tRNA guanine transglycosylase TGT E235Q mutant in complex with BDI (2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase | polymer | 386 | 42924.7 | 1 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis | tRNA-guanine transglycosylase, Guanine insertion enzyme, TGT |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE | non-polymer | 208.2 | 1 | Chemie (BDI) | |||
| 4 | D, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 5 | M (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Gln 235 | Glu 235 | engineered mutation |
| Lys 312 | Thr 312 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42924.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1102.5 | |
| All* | Total formula weight | 44027.2 |
