2Z1W

tRNA guanine transglycosylase TGT E235Q mutant in complex with BDI (2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE)

2Z1W の概要

• エントリーDOI: 10.2210/pdb2z1w/pdb
• 関連するPDBエントリー: 1P0B 2OKO 2Z1V 2Z1X
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE, ... (5 entities in total)
• 機能のキーワード: tgt, e235q mutant, bdi, bih, 2-butyl-5, 6-dihydro-1h-imidazo[4, 5-d]pyridazine-4, 7-dione, transferase
• 由来する生物種: Zymomonas mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44027.19

構造登録者

Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K. (登録日: 2007-05-16, 公開日: 2007-11-06, 最終更新日: 2023-11-01)

• 主引用文献: Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K.; Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies; J.Mol.Biol., 374:764-776, 2007; PubMed: 17949745; DOI: 10.1016/j.jmb.2007.09.062

実験手法

X-RAY DIFFRACTION (1.63 Å)