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2YPB

Structure of the SCL:E47 complex bound to DNA

Summary for 2YPB
Entry DOI10.2210/pdb2ypb/pdb
Related1HLH 2YPA
DescriptorT-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, EBOX FORWARD, ... (4 entities in total)
Functional Keywordsimmune system, hematopoiesis, leukemia
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus (By similarity): P17542
Nucleus: P15923
Total number of polymer chains4
Total formula weight27101.75
Authors
El Omari, K.,Hoosdally, S.J.,Tuladhar, K.,Karia, D.,Ponsele, E.,Platonova, O.,Vyas, P.,Patient, R.,Porcher, C.,Mancini, E.J. (deposition date: 2012-10-30, release date: 2013-07-31, Last modification date: 2023-12-20)
Primary citationEl Omari, K.,Hoosdally, S.J.,Tuladhar, K.,Karia, D.,Hall-Ponsele, E.,Platonova, O.,Vyas, P.,Patient, R.,Porcher, C.,Mancini, E.J.
Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4:135-, 2013
Cited by
PubMed: 23831025
DOI: 10.1016/J.CELREP.2013.06.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.87 Å)
Structure validation

217705

数据于2024-03-27公开中

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