2YPA
Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
Summary for 2YPA
Entry DOI | 10.2210/pdb2ypa/pdb |
Related | 1HLH 2XJY 2XJZ 2YPB |
Descriptor | T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, RHOMBOTIN-2, ... (7 entities in total) |
Functional Keywords | immune system, hematopoiesis, leukemia |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus (By similarity): P17542 Nucleus: P15923 Nucleus (Potential): P25791 Nucleus (Probable): Q86U70 |
Total number of polymer chains | 6 |
Total formula weight | 49615.56 |
Authors | El Omari, K.,Hoosdally, S.J.,Tuladhar, K.,Karia, D.,Ponsele, E.,Platonova, O.,Vyas, P.,Patient, R.,Porcher, C.,Mancini, E.J. (deposition date: 2012-10-30, release date: 2013-07-31, Last modification date: 2024-05-08) |
Primary citation | El Omari, K.,Hoosdally, S.J.,Tuladhar, K.,Karia, D.,Hall-Ponsele, E.,Platonova, O.,Vyas, P.,Patient, R.,Porcher, C.,Mancini, E.J. Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets. Cell Rep., 4:135-, 2013 Cited by PubMed: 23831025DOI: 10.1016/J.CELREP.2013.06.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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