2YPA
Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 | polymer | 91 | 10721.1 | 1 | UniProt (P17542) Pfam (PF00010) In PDB | HOMO SAPIENS (HUMAN) | TAL-1, CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 17, BHLHA17, STEM CELL PROTEIN, T-CELL LEUKEMIA/LYMPHOMA PROTEIN 5, SCL |
| 2 | B | TRANSCRIPTION FACTOR E2-ALPHA | polymer | 82 | 9674.2 | 1 | UniProt (P15923) Pfam (PF00010) In PDB | HOMO SAPIENS (HUMAN) | CLASS B BASIC HELIX-LOOP-HELIX PROTEIN 21, BHLHB21, IMMUNOGLOBULIN ENHANCER-BINDING FACTOR E12/E47, IMMUNOGLOBULIN TRANSCRIPT ION FACTOR 1, KAPPA-E2-BINDING FACTOR, TRANSCRIPTION FACTOR 3, TCF-3, TRANSCRIPTION FACTOR ITF-1, E47 |
| 3 | C | RHOMBOTIN-2 | polymer | 145 | 17007.6 | 1 | UniProt (P25791) Pfam (PF00412) In PDB | HOMO SAPIENS (HUMAN) | CYSTEINE-RICH PROTEIN TTG-2, LIM DOMAIN ONLY PROTEIN 2, LMO-2, T-CELL TRANSLOCATION PROTEIN 2, LMO2 |
| 4 | D | LIM DOMAIN-BINDING PROTEIN 1 | polymer | 51 | 5244.6 | 1 | UniProt (Q86U70) Pfam (PF17916) In PDB | HOMO SAPIENS (HUMAN) | LDB-1, CARBOXYL-TERMINAL LIM DOMAIN-BINDING PROTEIN 2, CLIM-2, LIM DOMAIN-BINDING FACTOR CLIM2, HLDB1, NUCLEAR LIM INTERACTOR, LDB1 |
| 5 | E | EBOX FORWARD | polymer | 11 | 3284.2 | 1 | HOMO SAPIENS | ||
| 6 | F | EBOX REVERSE | polymer | 11 | 3422.3 | 1 | HOMO SAPIENS | ||
| 7 | C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A: 180 - 253 (UniProt: P17542)
B: 535 - 613 (UniProt: P15923)
C: 25 - 156 (UniProt: P25791)
D: 300 - 339 (UniProt: Q86U70)
| PDB | External Database | Details |
|---|---|---|
| Met 163 | - | expression tag |
| Gly 164 | - | expression tag |
| Ser 165 | - | expression tag |
| Ser 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| Ser 173 | - | expression tag |
| Gln 174 | - | expression tag |
| Asp 175 | - | expression tag |
| Pro 176 | - | expression tag |
| Glu 177 | - | expression tag |
| Ile 178 | - | expression tag |
| Ser 179 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 532 | - | expression tag |
| Ala 533 | - | expression tag |
| Asp 534 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Ser 14 | - | expression tag |
| Ser 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Gln 23 | - | expression tag |
| Asp 24 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 289 | - | expression tag |
| Gly 290 | - | expression tag |
| Ser 291 | - | expression tag |
| Gly 292 | - | expression tag |
| Gly 293 | - | expression tag |
| His 294 | - | expression tag |
| Met 295 | - | expression tag |
| Gly 296 | - | expression tag |
| Ser 297 | - | expression tag |
| Gly 298 | - | expression tag |
| Gly 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 49353.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 49615.6 |
