2YN8

ephB4 kinase domain inhibitor complex

Summary for 2YN8

Entry DOI	10.2210/pdb2yn8/pdb
Related	2BBA 2VWU 2VWV 2VWW 2VWX 2VWY 2VWZ 2VX0 2VX1 2X9F 2XVD 4AW5 4BB4
Descriptor	EPHRIN TYPE-B RECEPTOR 4, STAUROSPORINE (3 entities in total)
Functional Keywords	transferase, unphosphorylated
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	67995.69
Authors	Read, J.,Brassington, C.A.,Overmann, R. (deposition date: 2012-10-13, release date: 2013-10-23, Last modification date: 2019-04-24)
Primary citation	Overman, R.C.,Green, I.,Truman, C.M.,Read, J.A.,Embrey, K.J.,Mcalister, M.S.B.,Attwood, T.K. Stability and Solubility Engineering of the Ephb4 Tyrosine Kinase Catalytic Domain Using a Rationally Designed Synthetic Library. Protein Eng.Des.Sel., 26:695-, 2013 Cited by PubMed: 23840071 DOI: 10.1093/PROTEIN/GZT032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation