2YN8
ephB4 kinase domain inhibitor complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2012-03-07 |
| Detector | RIGAKU CCD |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 51.635, 89.527, 81.087 |
| Unit cell angles | 90.00, 103.21, 90.00 |
Refinement procedure
| Resolution | 30.890 - 2.110 |
| R-factor | 0.1972 |
| Rwork | 0.195 |
| R-free | 0.23440 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.070 |
| Data reduction software | MOSFLM |
| Data scaling software | SCALEPACK |
| Phasing software | AMoRE |
| Refinement software | BUSTER (2.11.2) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 89.530 | 2.230 |
| High resolution limit [Å] | 2.110 | 2.110 |
| Rmerge | 0.100 | 0.400 |
| Number of reflections | 40603 | |
| <I/σ(I)> | 8.7 | 2.5 |
| Completeness [%] | 98.4 | 94.2 |
| Redundancy | 3.4 | 2.8 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7 | pH 7 |
