Crystal structure of the human Spir-1 KIND domain

Summary for 2YLF

DescriptorPROTEIN SPIRE HOMOLOG 1 (2 entities in total)
Functional Keywordsactin-binding protein, actin polymerization, spir, kinase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm, cytoskeleton  Q08AE8
Total number of polymer chains1
Total molecular weight25838.79
Zeth, K.,Pechlivanis, M.,Vonrhein, C.,Kerkhoff, E. (deposition date: 2011-06-01, release date: 2011-06-08, Last modification date: 2017-08-23)
Primary citation
Zeth, K.,Pechlivanis, M.,Samol, A.,Pleiser, S.,Vonrhein, C.,Kerkhoff, E.
Molecular Basis of Actin Nucleation Factor Cooperativity: Crystal Structure of the Spir-1 Kinase Non-Catalytic C-Lobe Domain (Kind)Formin-2 Formin Spir Interaction Motif (Fsi) Complex.
J.Biol.Chem., 286:30732-, 2011
PubMed: 21705804 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M111.257782
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2691002.2%8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload