2YHY

Structure of N-Acetylmannosamine kinase in complex with N- acetylmannosamine and ADP

Summary for 2YHY

Entry DOI	10.2210/pdb2yhy/pdb
Related	2YHW 2YI1
Descriptor	BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE, CHLORIDE ION, ZINC ION, ... (12 entities in total)
Functional Keywords	transferase, sugar kinase, sialic acid, rok family
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm (By similarity): Q9Y223
Total number of polymer chains	1
Total formula weight	38698.11
Authors	Martinez, J.,Nguyen, L.D.,Tauberger, E.,Hinderlich, S.,Reutter, W.,Fan, H.,Saenger, W.,Moniot, S. (deposition date: 2011-05-10, release date: 2012-02-29, Last modification date: 2023-12-20)
Primary citation	Martinez, J.,Nguyen, L.D.,Tauberger, E.,Hinderlich, S.,Reutter, W.,Fan, H.,Saenger, W.,Moniot, S. Crystal Structures of N-Acetylmannosamine Kinase Provide Insights Into Enzyme Specificity and Inhibition J.Biol.Chem., 287:13656-, 2012 Cited by PubMed: 22343627 DOI: 10.1074/JBC.M111.318170 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation