2YHY
Structure of N-Acetylmannosamine kinase in complex with N- acetylmannosamine and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE | polymer | 343 | 36639.0 | 1 | UniProt (Q9Y223) Pfam (PF00480) | HOMO SAPIENS (HUMAN) | N-ACETYL MANNOSAMINE KINASE, MANAC KINASE, UDP-GLCNAC-2-EPIMERASE/MANAC KINASE |
| 2 | B (A) | 2-acetamido-2-deoxy-alpha-D-mannopyranose | non-polymer | 221.2 | 1 | Chemie (BM3) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
| 5 | E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | F, I, M (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | G, J, K (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 8 | H (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | L (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 10 | N (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 11 | O (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 12 | P (A) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A: 406 - 720 (UniProt: Q9Y223)
| PDB | External Database | Details |
|---|---|---|
| Met 378 | - | expression tag |
| Gly 379 | - | expression tag |
| Ser 380 | - | expression tag |
| Ser 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| Ser 388 | - | expression tag |
| Ser 389 | - | expression tag |
| Gly 390 | - | expression tag |
| Leu 391 | - | expression tag |
| Val 392 | - | expression tag |
| Pro 393 | - | expression tag |
| Arg 394 | - | expression tag |
| Gly 395 | - | expression tag |
| Ser 396 | - | expression tag |
| His 397 | - | expression tag |
| Met 398 | - | expression tag |
| Glu 399 | - | expression tag |
| Asn 400 | - | expression tag |
| Leu 401 | - | expression tag |
| Tyr 402 | - | expression tag |
| Phe 403 | - | expression tag |
| Gln 404 | - | expression tag |
| Gly 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36639.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2059.1 | |
| All* | Total formula weight | 38698.1 |
