2YCY
TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL
Summary for 2YCY
Entry DOI | 10.2210/pdb2ycy/pdb |
Related | 1DEP 2VT4 2Y00 2Y01 2Y02 2Y03 2Y04 2YCW 2YCX 2YCZ |
Descriptor | BETA-1 ADRENERGIC RECEPTOR, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, octyl 1-thio-beta-D-glucopyranoside, ... (5 entities in total) |
Functional Keywords | gpcr, receptor, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, thermostabilising point mutations, seven-helix receptor, 7tm receptor |
Biological source | MELEAGRIS GALLOPAVO (TURKEY) |
Total number of polymer chains | 2 |
Total formula weight | 73645.07 |
Authors | Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. (deposition date: 2011-03-17, release date: 2011-06-08, Last modification date: 2023-12-20) |
Primary citation | Moukhametzianov, R.,Warne, T.,Edwards, P.C.,Serrano-Vega, M.J.,Leslie, A.G.W.,Tate, C.G.,Schertler, G.F.X. Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108:8228-, 2011 Cited by PubMed: 21540331DOI: 10.1073/PNAS.1100185108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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