2Y3P
Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8
Replaces: 2WL2Summary for 2Y3P
Entry DOI | 10.2210/pdb2y3p/pdb |
Descriptor | DNA GYRASE SUBUNIT A, MAGNESIUM ION, SIMOCYCLINONE D8, ... (4 entities in total) |
Functional Keywords | isomerase, aminocoumarin antibiotic |
Biological source | ESCHERICHIA COLI |
Cellular location | Cytoplasm : P0AES5 |
Total number of polymer chains | 2 |
Total formula weight | 119207.82 |
Authors | Edwards, M.J.,Flatman, R.H.,Mitchenall, L.A.,Stevenson, C.E.M.,Le, T.B.K.,Clarke, T.A.,McKay, A.R.,Fiedler, H.-P.,Buttner, M.J.,Lawson, D.M.,Maxwell, A. (deposition date: 2010-12-22, release date: 2010-12-29, Last modification date: 2023-12-20) |
Primary citation | Edwards, M.J.,Flatman, R.H.,Mitchenall, L.A.,Stevenson, C.E.M.,Le, T.B.K.,Clarke, T.A.,Mckay, A.R.,Fiedler, H.-P.,Buttner, M.J.,Lawson, D.M.,Maxwell, A. A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase. Science, 326:1415-, 2009 Cited by PubMed: 19965760DOI: 10.1126/SCIENCE.1179123 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
Download full validation report